Polynucleotides

Polynucleotides (PN) are natural DNA/RNA fragments, often derived from salmon or trout, that function as advanced injectable skin boosters to stimulate fibroblasts, increase collagen/elastin production, and improve skin hydration, texture, and elasticity. Primarily used for rejuvenation around the eyes, face, and neck, these biopolymers offer a highly biocompatible, regenerative, and non-invasive approach to treating fine lines, dark circles, and scars.

Key Aspects of Polynucleotides in Aesthetics

• Mechanism of Action: Unlike dermal fillers that provide immediate volume, polynucleotides act as "bio-stimulators" that repair skin at a cellular level, enhancing fibroblast viability and promoting long-term rejuvenation.
• Benefits: They increase collagen and elastin, reduce inflammation, promote skin healing, and treat crepey skin, acne scars, and pigmentation.
• Common Treatment Areas: They are particularly effective for the under-eye area (periorbital region), neck, décolletage, hands, and for scalp rejuvenation.
• Procedure Details: A course of 3–4 sessions, spaced 2–3 weeks apart, is typical, with results appearing 2–4 weeks after treatment and lasting 4–6 months.
• Safety & Composition: Derived from fish DNA, they are safe and biocompatible, though not suitable for those with severe fish allergies.
• Comparison to Fillers: While hyaluronic acid (HA) fillers provide instant volume, polynucleotides focus on deep-tissue regeneration and collagen stimulation.

Polynucleotides are often used to address aging signs like sagging, wrinkles, and dullness, providing a natural-looking, tighter skin appearance.